NMN is short for nicotinamide mononucleotide, and it is a molecule that naturally occurs in all forms of life. If we go deep at the molecular level, it is known as ribonucleotide, another basic structural component of nucleic acid RNA. NMN is the precursor of the essential molecule found in every cell known as NAD+, short for nicotinamide adenine dinucleotide. The NMN supplement is considered as the critical component to raise the levels of NAD+ in our bodies. You can learn the facts here now regarding the NMN supplementation for the body and how it gets absorbed and distributed in the body.
Synthesizing of NMN in the body
Before we hop on to how does NMN gets absorbed and distributed in the whole body, let us try and understand the process of how does NMN gets synthesized in the body. NMN gets produced from Vitamin B in the body. The enzyme present in Vitamin B responsible for NMN production in the body is called nicotinamide phosphoribosyltransferase (NAMPT). NAMPT is accountable for attaching nicotinamide ( a Vitamin B3) to PRPP that is a sugar-phosphate. There is another way too of production of NMN in the body. One can also make it out of “nicotinamide riboside” (NR) by adding a phosphate group. NAMPT acts as a rate-limiting enzyme for the production of NAD+. For this, more induction of NMN supplementation is suggested to raise the NAD+ levels.
How NMN supplements get absorbed and distributed throughout the body?
A molecular transporter is embedded in the surface of the cell, which helps in the smooth absorption of NMN supplements into the cells. The absorption is even smoother dues because the NMN molecule is smaller compared to the size of NAD+. Getting NAD+ absorbed into the body is not that easy due to the barrier in the cell membrane. This membrane hinders the entrance of any ions, large molecules, or polar molecules without any transporter due to the presence of waterless space present in it. Researchers primarily thought of changing NMN before it gets entered into the cells. Still, after discovering new evidence that NMN has a specific transporter in the cellular membrane, they changed their minds.
NMN has proved to increase the levels of NAD+ in many parts of the body, even in the pancreas, heart, blood vessels, and more. Hence, if any dysfunction in the body is found due to declined levels of NAD+, then induction of NMN is suggested as it gets absorbed and distributed quickly and also works quickly.
NMN does wonders by helping increase the NAD+ levels in the body. If you are still unsure about adding this supplement to your diet, then here is an important site to check for learning what benefits it has to offer.